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Safety and Immunogenicity of MVA85A in Volunteers Latently Infected With TB

Mise à jour : Il y a 4 ans
Référence : NCT00456183

Femme et Homme

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Extrait

This study is designed to evaluate the safety of MVA85A in healthy volunteers in the UK who are latently infected with M.tb. A single vaccination with MVA85A, when administeredat a dose of 5 x 107pfu intradermally, is safe in both mycobacterially naïve individuals and those previously vaccinated with BCG. We will use the same vaccination regime in this study. Subjects will be defined as being latently infected if they have a positive elispot response to ESAT6 or CFP10. Subjects will be identified from TB contact clinics.

Critère d'inclusion

  • Tuberculosis

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