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Kusajili – Centralise les essais cliniques mondiaux
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de votre recherche span> par promoteur : AstraZeneca AB
Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A double-blind, placebo-controlled, randomised, parallel-group, phase-II, multi-centre study to assess the efficacy, safety and tolerability of 4 twice daily doses and 2 once daily doses of AZD1981 given as tablets during 12 weeks in asthmatic patients treated with inhaled corticosteroids and long-acting-β2-agonists
The primary objective is to evaluate efficacy of AZD1981 compared with placebo in asthmatic patients treated with inhaled corticosteroids (ICSs) and long-acting β2- agonists (LABAs).
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A Long-Term, Post treatment, Safety Follow-up, Multi-Centre Study in Patients with Type 2 Diabetes Mellitus from the GALLANT, GALLEX or ARMOR Studies, G-PLUS (GALLANT, GALLEX and ARMOR - Post treatment Long-term follow-Up Study)
To investigate post treatment safety of patients with type 2 diabetes, who received randomized treatment in any of the treatment studies GALLANT, GALLEX or ARMOR by: 1. evaluating medical events and p...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
An International, Multicenter, Randomized, Double-blind, Parallel-group, Placebo-controlled, Active-controlled Study of the Efficacy and Safety of Sustained-release Quetiapine Fumarate (Seroquel SR™ ) in the Treatment of Generalized Anxiety Disorder (SILVER Study)
The primary objective of this study is to evaluate the efficacy of (SEROQUEL SR™ ) quetiapine fumarate sustained-release (SR) compared to placebo in the treatment of anxiety symptoms in patients with ...
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Essai clos aux inclusions
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Femme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A Phase I/II randomised, double-blind, multi-centre study to assess the efficacy of AZD2281 when given in combination with paclitaxel in the 1st or 2nd line treatment of patients with metastatic Triple Negative Breast Cancer
The primary objective of the Phase I part of this study is: · To establish the appropriate doses of paclitaxel and AZD2281 in combination, based on safety and tolerability (for use in the randomised P...
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A 12-Week, Randomised, Double-Blind, Placebo-Controlled, Parallel Group, Multinational, Phase IIb Study to Evaluate the Efficacy and Safety of 60 mg AZD9668 Administered Orally Twice Daily to Subjects with Chronic Obstructive Pulmonary Disease (COPD) on Treatment with budesonide/formoterol
To evaluate the efficacy of AZD9668 compared with placebo in symptomatic COPD subjects by assessing effect on lung function and symptoms of COPD.
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A Short-term 12-Week, Multi-centre, Randomized, Parallel-group, Double-blind, Placebo-controlled Study to Evaluate the Treatment Effect of Saxagliptin compared with Placebo in Adult Patients with Type 2 Diabetes and Renal Impairment (Moderate, Severe, and End-Stage) with an additional 40-week, Randomized, Parallel-group, Double-blind, Placebo-controlled Long-term Observational Period
Short-term: To evaluate the efficacy of saxagliptin 2.5 mg in adult patients with type 2 diabetes and renal impairment (moderate, severe and end-stage) compared with placebo by assessment of the absol...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A randomised, double-blind, phase III efficacy and safety study of cediranib (RECENTIN™ ) when added to cisplatin plus a fluoropyrimidine, compared with cisplatin plus a fluoropyrimidine alone, in patients with previously untreated, locally advanced or metastatic, unresectable Gastric Cancer (GC)
To determine the efficacy of cediranib when added to cisplatin plus a fluoropyrimidine compared to cisplatin plus a fluoropyrimidine alone by assessment of overall survival (OS).
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A Phase III Study of MEDI4736 versus Standard of Care in Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer Estudio de fase III de MEDI4736 frente al tratamiento estándar en pacientes con carcinoma pulmonar no microcítico localmente avanzado
To assess the efficacy of MEDI4736 treatment compared with Standard of Care in terms of Overall survival (OS) and Progression free survival (PFS). Evaluar la eficacia del tratamiento con MEDI473...
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unknown
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Femme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A Randomized, Open-label, Multicenter, Phase II Study Comparing the Effects on Proliferation and the Efficacy and Tolerability of Fulvestrant (FASLODEX™) 500 mg with Fulvestrant (FASLODEX™) 250 mg when given as Neoadjuvant Treatment in Postmenopausal Women with Estrogen Receptor Positive Breast Cancer (T2, 3, 4b, N0-3, M0)
To compare the effects of fulvestrant 500 mg and fulvestrant 250 mg on the proliferation marker Ki67 at 4 weeks
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A randomised, double blind, placebo controlled, parallel-group study with use of budesonide/formoterol “as-needed”, or terbutaline “as-needed” or regular use of budesonide + terbutaline “as-needed”, in patients with mild intermittent asthma
To evaluate the magnitude of the protective effect of the combination of budesonide and formoterol on an as-needed basis compared to the use of terbutaline as-needed on Exercise induced bronchoconstri...
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Essai clos aux inclusions
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