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Kusajili – Centralise les essais cliniques mondiaux
Résultat
de votre recherche span> par promoteur : AstraZeneca AB
Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A Phase II, Double-blind, Randomized Study to Compare the Efficacy of AZD2171 in Combination with 5-fluorouracil, Leucovorin, and Oxaliplatin (FOLFOX) and the Efficacy of Bevacizumab in Combination with FOLFOX in the Second-line Treatment of Patients with Metastatic Colorectal Cancer
Determine the efficacy of AZD2171 in combination with FOLFOX compared to efficacy of bevacizumab in combination with FOLFOX by assessment of PFS
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
Safety, Tolerability and Pharmacokinetics of 3 Dose regimens of AZD1446 vs. Placebo as an Add-on Treatment to Donepezil: A Multi-centre, Double-blind, Randomised, Placebo controlled, Parallel group Phase IIa Study in Patients with Mild to Moderate Alzheimer’s Disease during 4 weeks of Treatment
The primary objective of this study is to evaluate the safety and tolerability of 3 dose regimens of AZD1446 compared to placebo as an add-on treatment to donepezil for 4 weeks in patients with mild t...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A PHASE II MULTICENTRE RANDOMISED, PARALLEL GROUP, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF ZD1839 (IRESSA TM) (250MG TABLET) PLUS BEST SUPPORTIVE CARE (BSC) VERSUS PLACEBO PLUS BSC IN CHEMOTHERAPY-NAÏVE PATIENTS WITH ADVANCED (STAGE IIIB OR IV) NON-SMALL CELL LUNG CANCER (NSCLC) AND POOR PERFORMANCE STATUS
To compare ZD1839 + best supportive care (BSC) versus placebo + BSC in terms of progression-free survival
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A PHASE III RANDOMISED, STRATIFIED, PARALLEL-GROUP, MULTI-CENTRE, COMPARATIVE STUDY OF ZD1839 (IRESSA®) 250 MG AND 500 MG VERSUS METHOTREXATE FOR PREVIOUSLY TREATED PATIENTS WITH SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
To compare ZD1839 (250 mg and 500 mg) versus methotrexate in terms of overall survival
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A Phase 3, randomised, open-label, cross-over study to compare HFA vs CFC pMDI formulations of budesonide on methacholine hyper-reactivity in patients with stable, persistent, mild to moderate asthma
The primary objective is to compare the relative dose potency of HFA vs CFC pMDI budesonide on airway responsiveness to methacholine.
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
Ensayo clínico fase III, de 24 semanas de duración y 28 semanas de seguimiento, multicéntrico, aleatorizado, doble ciego, estratificado por edad, controlado con placebo para evaluar la eficacia y seguridad de dapagliflozina 10 mg una vez al día, en pacientes diabéticos tipo 2, con historia de enfermedad cardiovascular e hipertensión arterial, y que presenten mal control glucémico con su tratamiento habitual. A 24-week, multicentre, randomised, double-blind, age-stratified, placebo controlled phase III study with a 28-week extension period to evaluate the efficacy and safety of dapagliflozin 10 mg once daily in patients with type 2 diabetes, cardiovascular disease and hypertension, who exhibit inadequate glycaemic control on usual care
Comp. eficacia glucém. de dapaglif. 10 mg en comp. con placebo cuando se añade al tto. habitual de pac.con diabetes de tipo 2 con enferm. CV e hipertensión determinada como cambio medio de hemoglobina...
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A Parallel-Group, Multi-Centre, Active-Controlled (Glibenclamide) Long Term Extension Study to Evaluate the Safety and Tolerability of oral Tesaglitazar Therapy in Patients with Type 2 Diabetes Mellitus (GALLEX 4)
The primary objective of this study is to monitor the long-term safety and tolerability of tesaglitazar (0.5-1 mg) versus glibenclamide (2.5-15 mg), with or without other oral anti-diabetic drugs, whe...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A Phase I/II, Open Label, Multi-centre Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of the Tor Kinase Inhibitor AZD8055 Administered Orally to Patients with Advanced Solid Tumours, Lymphomas and Endometrial Carcinoma
To assess the safety and tolerability of AZD8055 in patients with advanced solid tumours or lymphomas (including 20 patients with endometrial carcinoma in Part B).
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A 24-Week Randomised, Double-blind, Parallel-group, Multi-centre, Placebo-controlled Phase III Study to Evaluate the Efficacy and Safety of Dapagliflozin in Combination with Glimepiride (a Sulphonylurea) in Subjects with Type 2 Diabetes who Have Inadequate Glycaemic Control on Glimepiride Therapy Alone
To assess the efficacy of dapagliflozin compared to placebo as add-on therapy to glimepiride in improving glycaemic control in subjects with type 2 diabetes, as determined by the change in A1C levels ...
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Essai clos aux inclusions
Plus d'informations
Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A 52-week, double-blind, randomised, multi-centre, parallel-group,Phase III study in patients 12 years and older with asthma, evaluating the efficacy and safety of Symbicort® (budesonide/formoterol) Turbuhaler® 160/4.5 μg ‘as needed’ compared with terbutaline Turbuhaler® 0.4 mg ‘as needed’ and with Pulmicort® (budesonide) Turbuhaler® 200 μg twice daily plus terbutaline Turbuhaler® 0.4 mg ‘as needed’
To demonstrate that Symbicort Turbuhaler 160/4.5 μg ‘as needed’ is superior to terbutaline Turbuhaler 0.4 mg ‘as needed’.
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unknown
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