A phase II study about interferon gamma 1b to therapy the steroid-refractory bronchiolitis obliterans after allogenic stem cell therapy

Mise à jour : Il y a 4 ans
Référence : EUCTR2010-022467-36

Femme et Homme

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Extrait

Objective improvement of lung function, i.e.: • Improvement of SO2, pO2 or pCO2 in oxygen dependent or improvement of FiO2 in ventilated patients ≥ 20 % or • Reduction of oxygen need in oxygen dependent patients ≥ 1L O2/min without deterioration of parameters in blood gas analysis (BGA) or • Improvement of obstructive parameters ≥ 20 % or • Improvement of lung function score (LFS) at least about one grade Improvement of lung function should be detectable at least by two consecutive examinations of lung function or BGA within at least four weeks.


Critère d'inclusion

  • steroid-refractory bronchiolitis obliterans

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