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Kusajili – Clinical trials directory
Result
of your search per specialist: Helen McShane
Woman and Man Max 99 years
Helen McShane, MD and PhD
Update Il y a 4 ans
A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers
This study is to assesss the safety and immunogenicity of vaccine based on Modified Vaccinia Ankara (MVA) expressing the 85A antigen (from Mycobacterium. tuberculosis). This vaccine is del...
Country
None
organs
None
Specialty
None
Closed trial
More information
Woman and Man Max 99 years
Helen McShane
Update Il y a 4 ans
Phase I Trial Evaluating Safety and Immunogenicity of MVA85A-IMX313 Compared to MVA85A in BCG Vaccinated Adults
This is a Phase I trial to evaluate the safety and immunogenicity of MVA85A-IMX313 vaccination compared to MVA85A vaccination, in BCG vaccinated adults.
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
Helen McShane
Update Il y a 4 ans
A BCG Challenge Model Study to Assess Anti-mycobacterial Immunity Induced by BCG and a Candidate TB Vaccine, MVA85A
The purpose of this study is to evaluate the BCG 'challenge' model a four-arm study design has been chosen. Twelve subjects will be recruited into each arm of the study. Allocation of BCG-...
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
Helen McShane
Update Il y a 4 ans
Study Evaluating Aerosol and Intradermal Administration of a Candidate Tuberculosis (TB) Vaccine, MVA85A, as a Way to Increase Immune Response and Avoid Anti-vector Immunity
Boost vaccinations sometimes have no effect because the body has got used to the vaccine and no longer reacts to it. We are therefore investigating whether vaccinating with aerosolised MVA...
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
Helen McShane, Dr
Update Il y a 4 ans
The Safety and Immunogenicity of a TB Vaccine; MVA85A, in Healthy Volunteers Who Are Infected With HIV
This study is designed to evaluate the safety of MVA85A in healthy volunteers in the UK who are infected with HIV. In phase I studies, a single vaccination with MVA85A, when administered a...
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
Helen McShane
Update Il y a 4 ans
Safety, Immunogenicity, and Impact of MVA85A, on the Immunogenicity of the EPI Vaccines
This study is preliminary to proving that this vaccine could protect against tuberculosis in humans. Although there is no proven data to show that infants will benefit directly from partic...
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
Helen McShane
Update Il y a 4 ans
Study of the Safety and Immunogenicity of Bacille Calmette Guerin (BCG) Vaccine
Tuberculosis (TB) kills about three million people annually. It is estimated that one third of the world's population are latently infected with Mycobacterium tuberculosis (M.tb). Multi-dr...
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
Helen McShane
Update Il y a 4 ans
Safety of Tuberculosis Vaccine, MVA85A, Administered by the Intramuscular Route and the Intradermal Route
This is a phase I study that will compare the safety and immunogenicity of candidate tuberculosis (TB) vaccine MVA85A administered by the intramuscular route and the intradermal route in h...
Country
United Kingdom
organs
None
Specialty
None
Closed trial
More information
Woman and Man Max 99 years
Helen McShane, MD and PhD
Update Il y a 4 ans
A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers Who Have Received BCG Immunisation 1 Month Previously
This is a phase I study to test the immunogenicity of a recombinant vaccine based on Modified Vaccinia Ankara (MVA) expressing the antigen 85A (from Mycobacterium tuberculosis). This vacci...
Country
United Kingdom
organs
None
Specialty
None
Closed trial
More information
Woman and Man Max 99 years
Helen McShane
Update Il y a 4 ans
Safety Study of ChAdOx1 85A Vaccination With and Without MVA85A Boost in Healthy Adults
This is a Phase I trial to evaluate the safety and immunogenicity of a ChAdOx1 85A vaccination with and without MVA85A boost in healthy BCG vaccinated adults.
Country
None
organs
None
Specialty
None
Closed trial
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