Remote Post-Conditioning (RPC) in renal transplantation Background and study aims In end-stage renal failure the usual functions of the kidney stop working. A kidney transplant is the best treatment, but it is important to find ways in which we can improve...

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Pharmacokinetic profile, safety and tolerability of Sildenafil (REVATIO®) in cardiac surgery patients with chronic kidney disease Background and study aims We are carrying out a study of 36 patients with kidney disease who are scheduled to have heart surgery. Our goal is to find the ideal dose of the drug named Sildenafil (REVAT...

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Study of the effectiveness of voriconazole in the treatment of Aspergillus fumigatus associated asthma Not provided at time of registration

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Transversus Abdominis Plane Block after laparoscopic live donor nephrectomy Background and study aims. Keyhole (laparoscopic) live donor kidney removal (nephrectomy) is now a well-established operation in the UK and Leicester was the first unit in the UK to perform this oper...

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The PRomotion Of Physical activity through structured Education with differing Levels of ongoing Support for those with pre-diabetes (PROPELS) Background and study aims Type 2 diabetes is an inability to adequately regulate blood glucose levels and currently affects over 2 million people in England alone and this number is predicted to rise ...

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Study to determine the pharmacokinetic profile, safety and tolerability of Sildenafil in cardiac surgery Background and study aims Acute kidney injury (AKI) occurs in up to one third of all patients after heart surgery. It causes rapid loss of kidney function, increases complications and risk of death af...

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