Combined wake and light therapy in children and adolescents with depression and affective dysregulation Background and study aims Chronotherapeutic treatments such as bright light therapy (BLT), wake therapy (WT) and sleep phase advance (SPA) have been successful for the treatment of adults with seasona...

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Stimulation of pudendal nerve for management of adult faecal incontinence using key hole surgery Background and study aims Faecal incontinence is the inability to control bowel movement, causing leakage of bowel contents from the back passage. It affects between 1-10% of adults, with 0.5-1% expe...

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The HAPI 'Hip Arthroscopy Pre-habilitation Intervention' study Background and study aims Hip arthroscopy is a keyhole technique used to gain access to the hip joint, and procedures can then be used to correct underlying femoro-acetabular impingement (a condition ...

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Randomised study for immunosuppression regimen in liver transplantation Not provided at time of registration

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The relationship between insomnia, negative affect, and paranoia Background and study aims Sleep problems and mental health complaints go hand-in-hand, with sleeping problems associated with many, if not all, mental health problems. This association is particularly...

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Effectiveness of an electronic food diary in weight reduction Background and study aims Weight loss can be difficult and lots of research has been done to find effective plan for improving weight loss programmes. It has been shown that if participants don't sti...

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Dark chocolate in pregnancy study Not provided at time of registration

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BOOST: A new pathway with BronchOscopic or Oesophageal ultrasound for lung cancer diagnosis and STaging http://www.cancerhelp.org.uk/trials/a-trial-of-endobronchial-ultrasound-or-endoscopic-ultrasound-to-diagnose-lung-cancer-and-see-how-far-it-has-spread

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A study to determine whether a single hormone injection a month before insertion of the contraceptive implant will reduce or stop irregular vaginal bleeding Not provided at time of registration

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Hearing aids, mild hearing loss and tinnitus Background and study aims Hearing aid technology has changed dramatically over the last decade with the use of miniaturised computer chips and improved plastics engineering. Both the structural design...

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