TNF-alpha Directed Therapy in Asthma This trial is a randomised, single-center, placebo-controlled, double blind, parallel group study in patients with asthma symptomatic on inhaled steroids. This trial will examine the effi...

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Repeat Nasal Allergen Challenge This is a non-drug, biomarker study to assess the utility of the model of repeated nasal allergen challenges in subjects with atopic rhinitis as a method of inducing an increased response ...

• Pays United Kingdom
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The Effects of OC000459 on Nasal Mediators This is the first proof of concept study for OC000459 and is undertaken to assess the effects of the compound on the development of inflammatory cytokines in a model (nasal allergen challe...

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Nasal LPS Challenge in Healthy Volunteers The purpose of this study is to develop a nasal challenge model that causes a mild degree of inflammation, without causing any pain or symptoms, but that allows us to measure a variety of ...

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