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Kusajili – Centralise les essais cliniques mondiaux
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de votre recherche par promoteur : University College Dublin
Femme et Homme Max 99 ans
University College Dublin Clinical Research Centre
MAJ Il y a 4 ans
Sickle cell anaemia is an inherited blood disorder which results in abnormal sickle shaped red blood cells which do not fit well through small blood vessels. These blockages prevent oxygen (in blood) from reaching different parts of the body resulting in painful crisis. This study will compare the effectiveness of two types of pain medication, one given through a vein and one squirted up the nose
The primary objective of this study is to illustrate the comparative efficacy of intranasal fentanyl to IV morphine in reducing severe pain associated with Painful Sickle Cell Crises in the Emergency ...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
University College Dublin
MAJ Il y a 4 ans
Dietary biomarkers of commonly consumed foods
Background and study aims Assessment of dietary intake is key to understand the links between diet and health. Here, researchers are going to study molecules in urine and blood samples to that them a...
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Femme Max 99 ans
University College Dublin CRC
MAJ Il y a 4 ans
A study of aspirin use in pregnancy to prevent high blood pressure and growth restriction of the fetus
To Determine : 1. Proportion of eligible women who agree to participate in the pilot study of a three arm randomised controlled trial 2. Compliance with the study protocol 3. Proportion of women in wh...
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Femme Max 99 ans
University College Dublin (Ireland)
MAJ Il y a 4 ans
Low dose aspirin with an early screening test for pre-eclampsia and fetal growth restriction
Background and study aims Pre-eclampsia is a condition that affects 2-8% of pregnancies. Previous studies have shown that aspirin can reduce the occurrence of pre-eclampsia in women with known risk f...
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Femme et Homme Max 99 ans
University College Dublin
MAJ Il y a 4 ans
An initial, short-duration study of vitamin D versus an inactive therapy on the ability of the human immune system to counteract the effects of Multiple Sclerosis on the brain and the effects of vitamin D on the immune system in healthy individuals
To determine the effects of vitamin D supplementation at two doses a) 4,667 IU daily b) 9,333 IU daily compared to c) placebo over a four and six-month period on the frequency of CD4 T cell subsets an...
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Femme et Homme Max 99 ans
University College Dublin
MAJ Il y a 4 ans
Discovery of novel biomarkers of food intake
Background and study aims Studies looking at the relationship between diet and health require ways of accurately measuring what a person consumes (dietary exposure). It can be very difficult to accura...
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Femme et Homme Max 99 ans
University College Dublin
MAJ Il y a 4 ans
The effects of self-directed walking and/or step training combined with a mobile phone based adaptive coaching system in type 2 diabetes mellitus
Background and study aims Type 2 diabetes mellitus (T2DM) is a long term condition where sufferers have difficulty controlling their blood sugar (glucose) as they do not produce enough insulin to func...
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Femme et Homme Max 99 ans
University College Dublin
MAJ Il y a 4 ans
The Use of Colchicine (an anti-inflammatory drug) in Prevention of Recurrent Stroke or heart attack after first Stroke; a randomised controlled trial El uso de colchicina (un fármaco anti-inflamatorio) en la prevención de ictus recurrentes o ataques al corazón después del primer accidente cerebrovascular; un ensayo controlado aleatorio
To investigate the efficacy of low dose colchicine (0.5mg/day) plus usual care (antiplatelet, lipid-lowering, antihypertensive treatment, and appropriate lifestyle advice) compared with usual care alo...
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Femme et Homme Max 99 ans
University College Dublin
MAJ Il y a 4 ans
A multicentre, interventional, parallel group, randomised, open-label, exploratory study to assess the earlier introduction of Ivabradine in the Management of Systolic Dysfunction Heart Failure. The QUALIVA study
To assess whether reducing heart rate with Ivabradine, versus further titration of beta blockade, in patients with HF-REF and borderline systolic blood pressure results in improved 6MWT
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Femme Max 99 ans
University College Dublin (Ireland)
MAJ Il y a 4 ans
The effects of exercise and vibration therapy on bone density and physical function in females aged 55-80 with osteoporosis
Background and study aims Osteoporosis is a condition that weakens bones, making them fragile and more likely to break. It is growing in prevalence and is proving costly for health care services. The...
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