Study of CS-1008 in Patients With Advanced Solid Malignancies and Lymphomas (Without Leukemic Component) This is a dose escalation study of CS-1008 (humanized anti-DR5 antibody) to determine the recommended Phase 2 dose and the maximum tolerated dose. Drug will be administered for six weeks a...

• Country United States
• organs None
• Specialty None

Efficacy Study of Maintenance Therapy for Ovarian Cancer Patients This study will assess the effect of IT-101 on delaying cancer progression in patients with platinum sensitive ovarian cancer.

• Country United States
• organs None
• Specialty None

The Efficacy of a Toothpaste to Reduce Sensitivity Hypersensitivity

• Country United States
• organs None
• Specialty None

A Study of AGN-195263 for the Treatment of Meibomian Gland Dysfunction This study will evaluate the safety and efficacy of AGN-195263 compared to vehicle in patients with meibomian gland dysfunction (MGD) in the eyelids.

• Country United States
• organs None
• Specialty None

Study of Erbitux™ (Cetuximab) in Pediatric Patients With Refractory Solid Tumors The purpose of this clinical research study is to establish the maximum tolerated dose and recommended Phase II dose of Erbitux™ in combination with Irinotecan in pediatric and adolescent ...

• Country United States
• organs None
• Specialty None

Study of Ticilimumab in Patients With Metastatic Colorectal Cancer Whose Disease Had Progressed After Treatment This study is for patients with metastatic adenocarcinoma arising from the colon or rectum who have received treatment(s) for metastatic disease with subsequent disease progression. Patien...

• Country Canada, United States
• organs None
• Specialty None

Safety, Reactogenicity and Immunogenicity of an H5N1 VLP This is a Phase I/IIa randomized, double-blind, placebo-controlled study to evaluate the safety, reactogenicity, and immunogenicity of 3 potencies (dosages) of H5N1 VLP vaccine or placebo ...

• Country United States
• organs None
• Specialty None

Safety and Efficacy of BKM120 in Relapsed and Refractory NHL This is a phase II study evaluating the safety, tolerability and efficacy of BKM120 in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL), mantle cell lymphoma (MCL...

• Country Belgium, France, Germany, Italy, Korea, Republic of, Spain, Turkey, United States
• organs None
• Specialty None

Safety, Tolerability, Pharmacokinetics And Measurement Of Whole Blood Activity (WBA) Of PNU-100480 After Multiple Oral Doses In Healthy Adult Volunteers The purpose of this study is to assess the safety, tolerability and pharmacokinetics of multiple doses of PNU-100480 given for 14 or 28 days. Killing activity against the bacterium that ca...

• Country United States
• organs None
• Specialty None

Assess the Effect of Daily Treatment of Vardenafil 20mg or Sildenafil 100mg and Placebo on Sperm Function Assess the effect of daily treatment of vardenafil 20mg or sildenafil 100mg and placebo on sperm function

• Country United States
• organs None
• Specialty None