The Effect of Intracameral Cefuroxime on Post-op Fibrin in Pediatric Cataract Surgery The study investigates whether placing an antibiotic inside the eye at the end of cataract surgery in children will reduce the amount of fibrin formation (fibrin formation can block the pu...

• Country Kenya
• organs None
• Specialty None

Endoscopic Prevention of Esophageal Cancer at Tenwek Hospital Esophageal cancer is common in Kenya. The precursor of esophageal cancer is esophageal squamous dysplasia (ESD). In this study, persons known to have ESD will undergo endoscopic removal or...

• Country Kenya
• organs None
• Specialty None

The use of albumin to prevent exchange blood transfusions and improve outcome in neonates with severe hyperbilirubinaemia Not provided at time of registration

• Country Kenya
• organs None
• Specialty None

A Phase IIA Trial to Evaluate the Safety and Immunogenicity of a DNA HIV-1 Vaccine Followed by an MVA HIV-1 Vaccine in HIV-uninfected Volunteers The purpose of this study is to evaluate the safety and tolerability of plasmid DNA and recombinant MVA (Modified Vaccinia Virus Ankara) in a prime-boost regimen. Approximately 111 volunt...

• Country Kenya, United Kingdom
• organs None
• Specialty None

Study of AERAS-402 in Healthy Infants AERAS-402 will be given to infants of at least 16 weeks of age who have already been vaccinated with BCG to determine if AERAS-402 will increase protection of infants to tuberculosis.

• Country Kenya, Mozambique, South Africa
• organs None
• Specialty None

Pre-Exposure Prophylaxis to Prevent HIV-1 Acquisition Within HIV-1 Discordant Couples Randomized, blinded, placebo-controlled trial to demonstrate if pre-exposure prophylaxis decreases HIV-1 acquisition among HIV-1 uninfected individuals within HIV-1 discordant couples.

• Country Kenya, Uganda
• organs None
• Specialty None