Establishing the Genetic Profile of Multiple Hereditary Exostoses (HME) in Families of BC The purpose of this study is to establish the genetic profile of families in British Columbia with HME.

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Gene Mutations and Orthopaedic Symptoms Correlation of Multiple Hereditary Exostoses: Multicentre Project The investigator's goal for this project is to examine the causes of the wide variability of the expression of Hereditary Multiple Exostoses (HME). Previous work completed by our group sho...

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Economic Evaluation of Clubfoot Treatment: One Centre's Experience Purpose: The purpose of the study is to complete a cost analysis of the different methods used for clubfoot treatment. Objectives: Short-term objective: To explore the exper...

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Using Botox to Treat Patients With Idiopathic Clubfoot The purpose of this study is to determine the effectiveness of treatment of idiopathic clubfoot utilizing Botulinum Toxin Type A (Botox). This is not a hypothesis-generating study as we ar...

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Genetic Linkage Study of Idiopathic Talipes Equinovarus (ITEV) (Clubfoot) The goal of this study is to identify and characterize the genetic loci causing idiopathic talipes equinovarus (clubfoot). The hypothesis is that a few genes account for a substantial fra...

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Trial of a Botulinum A Toxin (Botox) Injection in the Gastrocnemius Muscle in Children With Idiopathic Toe Walking The purpose of this study is to compare the effect of Botox and casting to placebo and casting for reducing toe walking problems in children who are idiopathic toe walkers.

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The Health-Related Quality of Life in Patients With Hereditary Multiple Exostoses The purpose of this study is to assess the health-related quality of life of subjects who have Hereditary Multiple Exostoses and to develop a disease specific quality of life survey. The i...

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