This study is designed to assess the efficacy and safety of filanesib + carfilzomib versus single-agent carfilzomib in patients with multiple myeloma who have received at least 2 prior lines of therap...

Update Il y a 4 ans
Reference: EUCTR2014-001052-39

This study is designed to assess the efficacy and safety of filanesib + carfilzomib versus single-agent carfilzomib in patients with multiple myeloma who have received at least 2 prior lines of therapy

Woman and Man

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Extract

Co-primary: • Compare progression-free survival (PFS) in patients treated with carfilzomib + filanesib and single-agent carfilzomib • Compare objective response rates (ORR) in patients with low serum alpha 1-acid glycoprotein (AAG) levels at Baseline treated with carfilzomib + filanesib and single-agent carfilzomib


Inclusion criteria

  • Multiple myeloma