Phase Ib/II study of efficacy and safety of MEK162 plus panitumumab in adult metastatic colorectal cancer patients with mutant or wild-type RAS tumors

Update Il y a 4 ans
Reference: EUCTR2013-001986-18

Woman and Man

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Extract

Phase Ib: To estimate the MTD and/or RP2D of MEK162 in combination with panitumumab Phase II: To assess clinical efficacy of the MEK162 and panitumumab combination


Inclusion criteria

  • Mutant RAS or wild-type (WT) RAS metastatic colorectal cancer