Study to test the safety and efficacy of Glasdegib (PF-04449913) versus placebo in patients with Myelofibrosis

Update Il y a 4 ans
Reference: EUCTR2014-001048-40

Woman and Man

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Extract

Lead-in Cohort • To assess the safety and tolerability of PF-04449913 in patients with primary or secondary MF who have been previously treated with ≥1 JAKi. Randomized Cohort • To compare the effect of PF-04449913 vs. placebo on SVR in patients with primary or secondary MF who have been previously treated with ruxolitinib.


Inclusion criteria

  • Myelofibrosis