A Phase 2 Study of Ruxolitinib in Combination With Pemetrexed/Cisplatin and for Treatment of Subjects With Advanced Lung Cancer Estudio Fase IIde Ruxolitinib en combinación con Pemetrexed/Cispla...

Update Il y a 4 ans
Reference: EUCTR2014-001436-10

A Phase 2 Study of Ruxolitinib in Combination With Pemetrexed/Cisplatin and for Treatment of Subjects With Advanced Lung Cancer Estudio Fase IIde Ruxolitinib en combinación con Pemetrexed/Cisplatino y Pemetrexed para el tratamiento de pacientes con cáncer de pulmón avanzado

Woman and Man

  • | Country :
  • -
  • | organs :
  • -
  • | Specialty :
  • -

Extract

?Part 1: To evaluate the safety and tolerability of ruxolitinib in combination with pemetrexed/cisplatin and select a dose for further evaluation ?Part 2: To evaluate and compare the OS of subjects with nonsquamous NSCLC that is Stage IIIB, Stage IV, or recurrent when treated with ruxolitinib or placebo in combination with pemetrexed/cisplatin and subsequently pemetrexed maintenance


Inclusion criteria

  • Nonsquamous NSCLC that is Stage IIIB, Stage IV, or recurrent,CPCNP no escamoso en estadio IIIB, estadio IV o recurrente