Woman and Man
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Extract
•To evaluate the levels of serum periostin in a population of patients with severe OCS-dependent asthma at Baseline • To examine the stability of serum periostin levels and individual patient phenotypes in relation to sputum eosinophils ( as defined by % eosinophils), blood eosinophil count, FeNO (ppb), lung function ( FEV1), and Asthma Control Questionnaire (ACQ-7) • To examine the changes in serum periostin levels in a study population with uncontrolled asthma that receives 7 days of high-dose OCS treatment and relate these changes to blood eosinophils, FeNO, lung function, AQLQ12+, and ACQ-7
Inclusion criteria
- Severe corticosteroid-dependent asthma