Mendelian Reverse Cholesterol Transport Study The purpose of this study is to investigate the use of radiolabeled particulate cholesterol administered intravenously in association with albumin, as a method to study reverse cholesterol...

• Country None
• organs None
• Specialty None

BMS Reverse Cholesterol Transport (RCT) Study The purpose of this study is to investigate the use of radiolabeled particulate cholesterol administered intravenously in association with albumin, as a method to study reverse cholesterol...

• Country United States
• organs None
• Specialty None

A Safety and Efficacy Study of AEGR-733 to Treat Homozygous Familial Hypercholesterolemia (FH) The goal of this trial is to study the effects of AEGR-733 on LDL cholesterol, other lipids as well as measures of safety over the long-term.

• Country None
• organs None
• Specialty None

Long Term, Follow-on Study of Lomitapide in Patients With Homozygous Familial Hypercholesterolemia This is a long term follow on study to assess the continued long term safety and efficacy of lomitapide in patients with homozygous familial hypercholesterolemia.

• Country Canada, Italy, South Africa, United States
• organs None
• Specialty None

Pharmacokinetic Drug Interactions of AEGR-733 on Lipid-lowering Agents This phase II, open-label research study was conducted in 129 healthy volunteers. Each subject will be given one initial oral dose of one of 7 FDA-approved medications (probe drugs), follo...

• Country None
• organs None
• Specialty None

Screening Protocol for a Gene Therapy Trial in Subjects With Homozygous Familial Hypercholesterolemia Homozygous Familial Hypercholesterolemia (HoFH) is a rare genetic metabolic disorder characterized by markedly elevated LDL-cholesterol (LDL-C) levels, resulting in severe atherosclerosis ...

• Country None
• organs None
• Specialty None

Reverse Cholesterol Transport (RCT) Study The purpose of this study is to investigate the use of radiolabeled particulate cholesterol administered intravenously in association with albumin, as a method to study reverse cholesterol...

• Country United States
• organs None
• Specialty None

A Gene Therapy Study for Homozygous Familial Hypercholesterolemia (HoFH) Homozygous Familial Hypercholesterolemia (HoFH) is a rare genetic metabolic disorder characterized by absent or severely reduced capacity to catabolize circulating LDL particles by the hep...

• Country None
• organs None
• Specialty None