Global assays for haemophilia Background and study aims Haemophilia A is an inherited clotting disorder primarily affecting males. It is caused by having a low level of a clotting factor called factor VIII (FVIII). Haemophilia B ...

• Country None
• organs None
• Specialty None

Prediction of preeclampsia/eclampsia in pregnant women Background and study aims Preeclampsia (PE) is a medical condition which can develop during pregnancy, and can affect both the mother and unborn baby. The exact cause of PE is not known, however it is...

• Country None
• organs None
• Specialty None

Assessing the length of Crohn's resection on disease recurrence Background and study aims Crohn’s disease affects any part of the digestive system, most commonly the last part of the small intestine. It usually results in narrowing of the bowel at this point which...

• Country None
• organs None
• Specialty None

A study comparing the effects of using an automated electronic system and a paper-based system of recording patients observations on the length of stay in a hospital for trauma patients Background and study aims In current practice, each time a set of observations (blood pressure, heart rate etc) are performed they are recorded on a paper chart. Each result is given a score. The scor...

• Country None
• organs None
• Specialty None

Physiotherapy Rehabilitation for Osteoporotic Vertebral fracture (PROVe) Background and study aims: 25,000 people in the UK have vertebral (spine) fractures related to their osteoporosis each year and many of these are referred for physiotherapy to help them recover after ...

• Country None
• organs None
• Specialty None

Lung imaging using hyperpolarized xenon gas MR imaging in patients with lung cancer after radiotherapy • To demonstrate that hyperpolarized Xe-129 is sensitive to change at 3 months following radiotherapy, and thus may be developed as an objective and quantifiable method of functional lung assessment i...

• Country None
• organs None
• Specialty None

Étude MErCuRIC1 : étude de phase 1 comparant l’efficacité du PD-0325901 associé au crizotinib par rapport au binimetinib associé au crizotinib, chez des patients ayant un cancer colorectal avec le gène RAS muté ou non et une expression anormale de c-MET. [Informations issues du site clinicaltrials.gov et traduites par l'INCa] [essai clos aux inclusions] Le cancer colorectal est le deuxième cancer le plus fréquent chez la femme et le troisième chez l’homme. Il touche le côlon et le rectum et se développe lentement pendant 5 à 10 ans avant de s’étendre...

• Country France
• organs Côlon ou Rectum (colorectal)
• Specialty Thérapies Ciblées

Oxidative stress and obstructive sleep apnoea; effect of withdrawing continuous positive airway pressure therapy Background and study aims Obstructive sleep apnoea (OSA) is a condition that causes interrupted breathing during sleep. It is unknown why patients with moderate/severe OSA develop high blood pressure,...

• Country None
• organs None
• Specialty None

A phase 2 trial of AZD1152 in relapsed/refractory diffuse large B-cell lymphoma To determine whether AZD1152 is an active anti-lymphoma agent in patients with the commonest type of aggressive lymphoma (DLBCL).

• Country None
• organs None
• Specialty None

Walk30X5: the development and feasibility evaluation of a physiotherapy walking programme for people with mild to moderate musculoskeletal conditions Background and study aims Physical activity is a public health issue. The majority of UK adults fail to meet recommended physical activity levels. People with long-term conditions related to muscles a...

• Country None
• organs None
• Specialty None