A Phase I Multiple Dose Pharmacokinetic Study of Nevirapine Extended Release (XR) in HIV-1 Infected Children The primary objective is to establish the pharmacokinetic (PK) profile at steady state of nevirapine XR in HIV infected children from >=3 to <18 years of age. This phase I trial is an open...

• Country Botswana, Germany, South Africa, United States
• organs None
• Specialty None

Efficacy and safety of artemeter-lumefantrine in the treatment of uncomplicated malaria-causing Plasmodium falciparum infections in Botswana

• Country Botswana
• organs None
• Specialty None

An international multicentre controlled clinical trial to evaluate high dose RIFApentine and a QUINolone in the treatment of pulmonary tuberculosis http://www.ctu.mrc.ac.uk/research_areas/study_details.aspx?s=49

• Country Botswana, Mozambique, South Africa, Zambia, Zimbabwe
• organs None
• Specialty None

Evaluating the Safety of Immediate Versus Deferred Isoniazid Preventive Therapy Among HIV-Infected Pregnant Women Tuberculosis (TB) is a leading cause of death among HIV-infected persons in low-income settings and can be a serious complication for HIV-infected pregnant women and their infants. Isoniaz...

• Country Botswana, Haiti, India, South Africa, Tanzania, United Republic of, Thailand, Uganda, Zimbabwe
• organs None
• Specialty None

Safety of and Immune Response to an HIV-1 Subtype C Vaccine (AVX101) in HIV Uninfected Adults The purpose of this study is to evaluate the safety of and immune response to an alphavirus replicon, HIV-1 subtype C gag vaccine, AVX101, in HIV uninfected adults in the United States, So...

• Country Botswana, South Africa, United States
• organs None
• Specialty None

evaluation of the lifestyle intervention

• Country Botswana
• organs None
• Specialty None

Safety of Cotrimoxazole in HIV- and HAART-exposed Infants The purpose of this study is to determine if prophylactic cotrimoxazole makes severe anemia or neutropenia more common in infants exposed to maternal HIV and combination antiretroviral the...

• Country Botswana
• organs None
• Specialty None