Femme et Homme
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Extrait
This study will evaluate the safety and efficacy of the combination of rituximab and methotrexate to treat disabling fibrosing skin disorders.Rituximab will be administered at baseline and month 6. The drug will be considered efficacious if the skin thickness diminishes substantially.
Critère d'inclusion
- Debilitating Fibrosing Skin Disorders (Localised Scleroderma, Eosinophilic Fasciitis)