Femme et Homme
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Extrait
1. To evaluate safety, tolerability and pharmacokinetics of multiple doses of PF-04360365 administered monthly (approximately every 30 days; Cohort M) or every 3 months (approximately every 90 days; Cohort Q) for approximately one year in subjects with mild-to-moderate AD. 2. To assess the effect of multiple doses of PF-04360365 on brain amyloid burden in the subjects dosed monthly (Cohort M) for approximately one year in subjects with mild-to-moderate AD. 3. To characterize the effect of PF-04360365 on CSF Aβ during dosing for approximately one year.
Critère d'inclusion
- mild to moderate Alzheimer's Disease