Randomized, Phase 2 Study of FOLFOX or FOLFIRI with AG-013736 or Bevacizumab in Patients with Metastatic Colorectal Cancer after Failure of an Irinotecan or Oxaliplatin-containing First-line Regimen

Mise à jour : Il y a 4 ans
Référence : EUCTR2007-006283-30

Femme et Homme

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Extrait

To demonstrate that the combination of AG-013736 with either FOLFIRI or FOLFOX is superior to FOLFIRI or FOLFOX in combination with bevacizumab in prolonging the PFS in the second-line treatment of patients with metastatic CRC after failure of an irinotecan or oxaliplatin-containing first-line regimen.


Critère d'inclusion

  • Second line treatment of patients with metastatic carcinoma of colon and rectum