A Multinational Study to Evaluate the Safety and Activity of Enzalutamide in Combination With Exemestane in Women With Hormone-Positive Breast Cancer That Is Normal for HER-2

Update Il y a 4 ans
Reference: EUCTR2013-002717-35

Woman Man

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Extract

To determine the benefit of exemestane plus enzalutamide versus exemestane plus placebo as assessed by progression free survival (PFS) in patients with advanced breast cancer that is estrogen and/or progesterone receptor positive and human epidermal growth factor receptor 2 (HER2) normal and in the subset of patients with a genomic signature of differential gene expression based on RNA sequencing (Dx).


Inclusion criteria

  • Breast Cancer