Extrait

Background and study aims Cardiac output is the volume of blood pumped by the heart per minute. Monitoring the cardiac output to guide fluid administration has been shown to benefit patients undergoing major colorectal surgery, improving their outcomes and reducing the length of hospital stay. The aim of this study is to detect any differences in patient outcome with the use of the LiDCOrapid monitor compared with conventional oesophageal Doppler monitoring. Who can participate? Patients undergoing elective colorectal surgery. What does the study involve? Both monitors are set up and the participant is randomly allocated to have their fluid administration guided by either LiDCOrapid or oesophageal Doppler. The anaesthetist is not able to see the measurements from the other monitor, but paired measurements are taken throughout. Patient outcomes are collected during their hospital stay and follow-up. What are the possible benefits and risks of participating? There is established evidence behind the use of both LiDCO and oesophageal Doppler monitoring and both are already in widespread use. An interim analysis will take place once half of the participants have been recruited to avoid harm if significant differences in outcome are detected. Where is the study run from? St Thomas' Hospital (UK) When is the study starting and how long is it expected to run for? May 2011 to October 2013 Who is funding the study? Guy's and St Thomas' Charity (UK) Who are the main contacts? Mr Jonathan van Dellen (Research Fellow) - [email protected] Mr Andrew Williams (Consultant Colorectal Surgeon) Dr Stuart McCorkell (Consultant Anaesthesist)

Critère d'inclusion

• Improving perioperative care for elective colorectal surgery

Liens

• isrctn
• ictrp