DORADO-AC - Optimized Doses of Darusentan as Compared to an Active Control in Resistant Hypertension A Phase 3 Randomized, Double-Blind, Placebo- and Active-Controlled, Multi-center, Parallel Group ...

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Reference: EUCTR2006-003547-23

DORADO-AC - Optimized Doses of Darusentan as Compared to an Active Control in Resistant Hypertension A Phase 3 Randomized, Double-Blind, Placebo- and Active-Controlled, Multi-center, Parallel Group Study to Evaluate the Safety and Efficacy of Darusentan in Subjects with Resistant Hypertension Receiving Combination Therapy with Three or More Antihypertensive Drugs, Including a Diuretic, as Compared to Guanfacine or Placebo

Woman and Man

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Extract

The primary objective of this study is to determine if darusentan is effective in reducing SBP and DBP in subjects who have RHTN, despite being treated with full doses of three or more antihypertensive drugs, including a diuretic.


Inclusion criteria

  • Resistant hypertension