A Worldwide, Multicenter, Double-Blind, Randomized, Parallel Study to Evaluate the Efficacy of MK-0524 to Improve Tolerability of Extended Release Niacin

Update Il y a 4 ans
Reference: EUCTR2006-003107-39

Woman and Man

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Extract

To demonstrate the efficacy of MK-0524 to protect against niacin-induced flushing in patients who resume therapy with either MK-0524A 2g or ER-niacin 2g after a 5 day drug holiday from a stable dose of MK-0524A 2g. MK 0524A will produce less flushing that ER-niacin as measured by maximum Global Flushing Severity Score (GFSS) categorised into none/mild, moderate, severe, extreme during the first 7 days following a 5-day holiday.


Inclusion criteria

  • Hypercholesterolemia