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A non-randomized, multiple dose, three treatment period, open-label, single sequence, single group study to evaluate the pharmacokinetic effect of two doses of QTI571 (imatinib) on the co-administe...

Update Il y a 4 ans
Reference: EUCTR2010-021344-17

A non-randomized, multiple dose, three treatment period, open-label, single sequence, single group study to evaluate the pharmacokinetic effect of two doses of QTI571 (imatinib) on the co-administered drugs sildenafil and bosentan in pulmonary arterial hypertension (PAH) patients

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Extract

To investigate the effect of two dose levels of QTI571 on the pharmacokinetics of the coadministered drugs sildenafil and bosentan at steady-state in patients with pulmonary arterial hypertension.

Inclusion criteria

  • Pulmonary Arterial Hypertension (PAH)

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