Exercise Intervention for Multiple Sclerosis: the Sheffield ExIMS trial

Mise à jour : Il y a 4 ans
Référence : ISRCTN41541516

Femme et Homme

  • | Pays :
  • -
  • | Organes :
  • -
  • | Spécialités :
  • -

Extrait

Background and study aims Multiple sclerosis (MS) is one of the most common diseases of the central nervous system (brain and spinal cord) in young adults. Healthy nerves are coated in a fatty casing (myelin sheath) which helps messages to travel quickly and smoothly along them. When a person is suffering from MS, the immune system, which normally helps to protect against infection, attacks and gradually destroys the myelin sheath (demyelination). This means that messages cannot travel along the nerves effectively causing a range of disabilities. A number of recent studies have shown that exercise is an effective way of improving functioning and mobility in people suffering from MS. The aim of this study is to investigate the effectiveness of a 12-week exercise programme in patients with mild to moderate MS. Who can participate? Adults with MS who are able to walk a distance of 10 meters. What does the study involve? Participants are randomly allocated to one of two groups. Those in the first group take part in a 12 week exercise programme. This involves two supervised and one home-based session per week for six weeks and then one supervised and two home-based sessions per week for six weeks. The sessions take place in small groups and involve short bouts of low to moderate intensity exercise. Those in the second group continue with their normal support alone during the study. At the start of the study and then again after 12 weeks and a further six months, participants in both groups complete a walking test to assess their abilities and complete a number of questionnaires in order to find out if their quality of life and other MS symptoms have improved. What are the possible benefits and risks of participating? Not provided at time of registration Where is the study run from? Centre for Sport and Exercise Science, Sheffield Hallam University (UK) When is the study starting and how long is it expected to run for? January 2009 to January 2012 Who is funding the study? Multiple Sclerosis Society (UK) Who is the main contact? Dr John Saxton [email protected]


Critère d'inclusion

  • Multiple sclerosis

Liens