A study to investigate the safety and tolerability of a 14 day oral treatment with different doses of BAY 1142524 in comparison to placebo in patients with left-ventricular dysfunction after myocardia...

Mise à jour : Il y a 4 ans
Référence : EUCTR2014-005297-12

A study to investigate the safety and tolerability of a 14 day oral treatment with different doses of BAY 1142524 in comparison to placebo in patients with left-ventricular dysfunction after myocardial infarction

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Extrait

The primary objective of this pilot study is to investigate the safety and tolerability after multiple oral doses of BAY 1142524 administered BID (using 3 dose groups) or OD (using a 4th dose group) as combinations of 5 and 50 mg IR tablets for 14 days in 12 patients with left-ventricular dysfunction after myocardial infarction (9 verum and 3 placebo) per dose group in comparison to placebo in a randomized, single blind group-comparison design.


Critère d'inclusion

  • left-ventricular dysfunction after myocardial infarction