Extrait

Background and study aims? Cardiac arrest happens when the heart suddenly stops pumping blood around the body. This is a medical emergency as damage to the brain and other organs can lead to death very soon afterwards. The brain is particularly sensitive to a lack of oxygen with brain cells beginning to die after about 4 minutes. There is an ongoing discussion as to which kind of airway device used during resuscitation attempts in patients having a cardiac arrest outside of hospital (out-of hospital cardiac arrest) is most likely to result in survival of the patient and with minimal/no damage to the brain. The endotracheal tube (a tube inserted into the windpipe though the mouth or nose) is still considered the “gold standard” method of securing an airway and therefore delivering oxygen to the body in cases of cardiac arrest. However, there are also several supraglottic airway devices (breathing devices that sit on the larynx or voice box) available. The laryngeal tube in particular is now widely used. Some studies suggest that the laryngeal tube and other supraglottic airway devices may not be as successful as the endotracheal tube in preventing brain damage after an out-of hospital cardiac arrest. Here, we will compare the performance of the endotracheal tube and laryngeal tube during after an out-of hospital cardiac arrest. This will be done by analysing the amount of oxygen in the blood during resuscitation and also once the resuscitation is successful (that is when the patient’s heart begins to beat normally and they start breathing again). Who can take part? Adult patients with an age of over 18 years, suffering from out-of hospital cardiac arrest. Cardiac arrest should be witnessed and of presumed cardiac origin (determined by the emergency physician). What does the study involve? Patients suffering from an out-of hospital cardiac arrest are randomly allocated to one of two groups. Those in group 1 are treated using the laryngeal tube. Those in group 2 are treated using the endotracheal tube. Ten minutes after the airway has been secured a sample of blood from an artery is taken to measure the amount of gas (for example oxygen) it contains. Once the patient has been admitted to hospital, another blood sample is taken to see whether there are any changes to the arterial blood gases depending on the airway device used. What are the possible benefits and risks of participating? We expect no extraordinary risk to the patient. The arterial puncture procedure used to collect the blood sample is performed in every patient in a critical condition when arriving the emergency department. Where is this study run from? Department of Emergency Medicine of the Medical University of Vienna (Austria) When is the study starting and how long is it expected to run for? January 2015 to December 2015 Who is funding the study? The Medical University of Vienna (Austria) Who is the main contact? Dr. Raphael van Tulder mailto:[email protected]

Critère d'inclusion

• Cardiopulmonary resuscitation, airway management

Liens

• ictrp
• isrctn