A Phase 2 Study of XL147 in Subjects with Advanced or Recurrent Endometrial Carcinoma

Mise à jour : Il y a 5 ans
Référence : EUCTR2009-016707-30

Femme Homme

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Extrait

The primary objectives of this study are: • To estimate the efficacy endpoints of: 1) ORR (confirmed complete response [CR] or confirmed PR), and 2) rate of 6-month PFS (PFS6) of XL147 in relation to the presence or absence of tumor PI3K pathway alterations (ie, molecular alterations that directly affect the PI3K pathway: PIK3CA mutation/amplification and/or PTEN deficiency) in subjects with advanced or recurrent EC • To evaluate the safety and tolerability of XL147 in this population


Critère d'inclusion

  • The purpose of this study is to assess the efficacy and safety of XL147 in subjects with Advanced or Recurrent Endometrial Carcinoma