Computer Guided Doing of Tacrolimus in Renal Transplantation

Update Il y a 4 ans
Reference: NCT02010320

Woman and Man

  • | Country :
  • Norway
  • | organs :
  • -
  • | Specialty :
  • -

Extract

Dosing of tacrolimus is challenging due to the large inter-individual variation in its pharmacokinetics. The investigators have developed a pharmacokinetics population model that can be used to estimate individual doses of tacrolimus in renal transplant recipients. The model will be prospective tested in a randomized clinical trial. The hypothesis is that the computer model is superior to experienced transplant physicians in reaching and keeping the patients in the target range of tacrolimus.


Inclusion criteria

  • renal transplantation

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