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This protocol describes a total of three studies that are intrinsically linked. It does therefore have three titels. 1. The effect of xenon and sevoflurane on depth of hypnosis monitors when titrated ...

Mise à jour : Il y a 4 ans
Référence : EUCTR2008-004132-20

This protocol describes a total of three studies that are intrinsically linked. It does therefore have three titels. 1. The effect of xenon and sevoflurane on depth of hypnosis monitors when titrated to standard anaesthesia parameter. 2. The efficacy of dexamethasone for prevention of PONV after xenon or sevoflurane. 3. Ondansetron as rescue for the treatment of established PONV after xenon or sevoflurane

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Extrait

1. To compare the effect of xenon or sevoflurane on the depth of hypnosis as assessed by the Bispectral Index (BIS) and the Composite Auditory Evoked Potential Index (cAAI) when titrated according to standard clinical parameter. 2. To demonstrate that dexamethasone prevents PONV equally well after xenon or sevoflurane. 3. To determine the onset-time of ondansetron when used as rescue medication for postoperative nausea and vomiting.

Critère d'inclusion

  • 1. The effect of xenon and sevoflurane on depth of hypnosis monitors when titrated to standard anesthesia parameter. 2. The efficacy of dexamethasone for prevention of PONV after xenon or sevoflurane. 3. Ondansetron as rescue for the treatment of established PONV after xenon or sevoflurane

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