A Randomized, Placebo-Controlled Trial of Carboplatin and Paclitaxel With or Without ABT-888 in Metastatic or Locally Advanced Unresectable Breast Cancer

Mise à jour : Il y a 4 ans
Référence : EUCTR2014-000345-70

Femme et Homme

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Extrait

The primary endpoint is to assess the progression-free survival (PFS) of veliparib in combination with carboplatin (C) and paclitaxel (P) compared to placebo with C/P in subjects with a BRCA1 and/or BRCA2 Mutation and in Her-2 Negative Metastatic or Locally Advanced Unresectable Breast Cancer


Critère d'inclusion

  • HER2-Negative Metastatic or Locally Advanced Unresectable BRCA-Associated mutation (BRCA1 and BRCA2) Breast Cancer