Pharmacokinetic-pharmacodynamic modeling of S(+)-KETamine in healthy volunteers Not provided at time of registration

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Influence of intravenous versus oral administration, arterial versus venous sampling and gender on pharmacokinetic-pharmacodynamic modelling of morphine and morphine-6-glucuronide-induced pain relief in healthy volunteers Not provided at time of registration

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Onset of analgesia with OxyNorm Instant in healthy volunteers Background and study aims Acute and breakthrough pain (sudden additional acute pain on top of the long-term pain) is difficult to treat, especially since the pain requires immediate relief. Various dr...

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Reversal of the respiratory effect of morphine and morphine-6-glucuronide by naloxone: a clinical study using healthy volunteers Not provided at time of registration

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