Impact of Hot Flashes on Sleep and Mood Disturbance We plan to enroll 60 healthy, non-pregnant premenopausal women age 18-45 who do not have hot flashes (in order to have 30 women complete all study procedures) in a trial investigating the ...

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Effects of Estrogen and Hot Flashes on Mood in Postmenopausal Women This protocol is a controlled study of estradiol therapy in early postmenopausal women with and without frequent hot flashes that will be used to determine whether hot flashes are an impor...

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Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia This study will evaluate the effectiveness of estrogen replacement therapy in treating depression in menopausal women with hot flashes and insomnia.

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Effect of Nuvigil on Fatigue The purpose of this study is to determine if armodafinil improves quality of life and is an effective treatment of fatigue in symptomatic perimenopausal and postmenopausal women.

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The Oral Contraceptive Pill for Premenstrual Worsening of Depression To determine if augmentation with the oral-contraceptive pill containing drospirenone and ethinyl estradiol is more effective than placebo in the treatment of premenstrual breakthrough of ...

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