Diagnosis and Treatment Planning in Patients Suspected of Having Lung Cancer RATIONALE: Diagnostic procedures and treatment-planning systems may affect outcome in patients suspected of having lung cancer. PURPOSE: Randomized diagnostic trial to compare the effecti...

• Country United Kingdom
• organs None
• Specialty None

The effect of targeted exercise on falls and function for people with Parkinson's disease (Group Exercise Trial for Parkinson's disease - GET uP study) Not provided at time of registration

• Country United Kingdom
• organs None
• Specialty None

Psychological treatments for severe and complex mental health problems/personality disorder. A phase II randomised controlled trial Not provided at time of registration

• Country United Kingdom
• organs None
• Specialty None

A Study to Quantify Bacille Calmette Guerin (BCG) and Characterise the Immune Response After BCG Vaccination This is a human pilot study of 16 healthy BCG-naïve volunteers to quantify BCG from the BCG vaccination site. Volunteers will be vaccinated with BCG. The first 8 will go on to have a punch...

• Country United Kingdom
• organs None
• Specialty None

A randomised study of continuous infusional 5-fluorouracil with or without bolus mitomycin-C in patients with advanced colorectal cancer Not provided at time of registration

• Country United Kingdom
• organs None
• Specialty None

Trial of Articaine for Peribulbar Anaesthesia Not provided at time of registration

• Country United Kingdom
• organs None
• Specialty None

Safety, Tolerability and Pharmacokinetic Study in Healthy Subjects by Dermal Application of a LEO 29102 The principal aim of this study is to obtain safety, tolerability and pharmacokinetic data when LEO 29102 is administered cutaneously as single and multiple doses to healthy subjects. The...

• Country United Kingdom
• organs None
• Specialty None

Improving symptoms of intermittent claudication in patients with erectile dysfunction and peripheral vascular disease: a pilot study assessing the benefit of daily dosing with Cialis (tadalafil) 10 mg Not provided at time of registration

• Country United Kingdom
• organs None
• Specialty None

Does Sildenafil Protect Against Pulmonary Related Complications Following Cardiopulmonary Bypass? Does pre-operative administration of Sildenafil (Viagra, Pfizer) reduce the lung injury associated with cardiopulmonary bypass in children undergoing corrective surgical repair of congenit...

• Country United Kingdom
• organs None
• Specialty None

Phase II Trial Evaluating Irinotecan and Capecitabine Relapsed/Refractory Upper GI Tumours The objective of this study is to assess the efficacy and toxicity of a 3 weekly regimen containing irinotecan combined with capecitabine in the setting of relapsed or refractory upper gas...

• Country United Kingdom
• organs None
• Specialty None