Immunogenicity and Safety Study of a GSK Influenza Vaccine Candidate in Adults The purpose of this study is to evaluate the safety and immunogenicity of GSK influenza vaccine candidate compared to a licensed trivalent influenza vaccine in adults.

• Pays Czech Republic
• Organes Aucun
• Spécialités Aucune

Case Control Study of Pharmacogenomic Factors Associated With Hepatocellular Injury Following Exposure to Lapaquistat Acetate The purpose of this study is to examine the genetic contribution to the mechanism of lapaquistat acetate- induced hepatic abnormalities.

• Pays Argentina, Canada, Chile, Czech Republic, Finland, Germany, Latvia, Netherlands, Poland, Russian Federation, Slovakia, South Africa, United Kingdom, United States
• Organes Aucun
• Spécialités Aucune

Evaluating Efficacy of Canakinumab (ACZ885) in Prevention of Acute Flares in Chronic Gout Patients Initiating Allopurinol Therapy A 24-week, dose-ranging, multi-center, double-blind, double-dummy, active-controlled study to evaluate canakinumab (ACZ885) for prophylaxis of signs and symptoms of acute flares in chronic...

• Pays Argentina, Belgium, Colombia, Czech Republic, Germany, Guatemala, Hungary, Poland, Portugal, Russian Federation, Singapore, Slovakia, South Africa, Spain, Taiwan, Province of China, Turkey, United Kingdom, United States
• Organes Aucun
• Spécialités Aucune

The SEPIA-PCI Trial: Otamixaban in Comparison to Heparin in Subjects Undergoing Non-Urgent Percutaneous Coronary Intervention The objective of this dose-ranging study is to determine the effects of several intravenous (IV) regimens of otamixaban on pharmacodynamic markers (including markers of thrombosis and coag...

• Pays Belgium, Canada, Czech Republic, France, Germany, Netherlands, Slovakia, South Africa, Spain, United States
• Organes Aucun
• Spécialités Aucune

Thoratec Corporation HeartMate PHP™ Cardiogenic Shock Trial The primary objective of this study is to assess reasonable safety and performance of the HeartMate PHP to provide hemodynamic support for up to 72 hours in patients with cardiogenic shock...

• Pays Czech Republic, Germany, Hungary, Netherlands
• Organes Aucun
• Spécialités Aucune

To Compare the Efficacy and Safety of a Therapy of Tacrolimus With Sirolimus or MMF in Kidney Transplantation Primary objective of this study is to compare the two therapy regimens with regard to renal function by using calculated creatinine clearance. The secondary objectives are to compare the e...

• Pays Australia, Austria, Belgium, Czech Republic, France, Germany, Hungary, Italy, Netherlands, Poland, Romania, Spain, Sweden, United Kingdom
• Organes Aucun
• Spécialités Aucune

Effect of Moderate Hepatic Impairment on the Pharmacokinetics and Metabolism of a Single Dose of Licarbazepine This study will assess the influence of moderate hepatic impairment on the pharmacokinetics of licarbazepine after single oral administration in healthy subjects and in subjects with stabl...

• Pays Czech Republic
• Organes Aucun
• Spécialités Aucune

Immunogenicity and Safety of a Cell-derived Influenza Vaccine in Elderly A controlled, double-blind study to determine the immunogenicity and safety of influenza cell derived vaccine in elderly subjects.

• Pays Czech Republic, Estonia, Lithuania
• Organes Aucun
• Spécialités Aucune

Safety and Efficacy of Eslicarbazepine Acetate as Adjunctive Therapy for Partial Seizures in Elderly Patients This is an open Label study to investigate the safety and efficacy of eslicarbazepine acetate as adjunctive therapy for partial seizures in elderly patients.

• Pays Austria, Bulgaria, Croatia, Czech Republic, France, Germany, Poland, Portugal, Romania, Spain
• Organes Aucun
• Spécialités Aucune

Compare the Immune Response & Safety Elicited by Henogen's Adjuvanted Hepatitis B Vaccine vs Aventis Pasteur MSD's Hepatitis B Vaccine in Pre-Dialysis & Dialysis Patients Who Did Not Respond to Previous Hepatitis B Vaccination Hepatitis B prevention in non-responders uraemic patients is currently based on both HBsAg surveillance and the isolation from HBsAg carriers. A more immunogenic vaccine would be a benefit...

• Pays Belgium, Czech Republic, Hungary
• Organes Aucun
• Spécialités Aucune